What Skincare Products Do Not Mix?

Posted on December 15 2022

What Skincare Products Do Not Mix?

What skincare products do not mix?

You've probably experienced the frustration of accidentally putting a product on your face only to find it will cause an allergic reaction or irritation. I know I have. The worst part is that you have to wait for your skin to calm down before you can try again, which means wasted money and more time spent waiting in front of the mirror wondering whether your skin will ever look normal again.


Retinol and vitamin C can't mix, because they're both antioxidants. Vitamin C is water soluble, while retinol is oil soluble; when you put them together in your skin (which is mostly water), the two chemicals don't fully dissolve and can break down each other's molecules.

You might be wondering why you would want to use both of these powerful ingredients at once anyway—and that's a fair question! In addition to being an antioxidant, retinoids help boost collagen production by encouraging cell turnover in the dermis layer of your skin. They also function as exfoliants by stimulating cell regeneration in deeper layers of your epidermis to help smooth out fine lines or wrinkles without damaging precious skin tissue!


As you know, acids are very effective for removing dead skin cells and exfoliating the surface of your skin. But if you're new to the sloughing game, there are a few things you should keep in mind before mixing acids with other products. Acids will react with certain ingredients—like vitamin C, retinol and niacinamide—so read on for tips on how not to break chemistry's rules of order!

It's best to use an acid-based product alone or only after one hour after applying a vitamin C formula. This is because vitamin C can react with an acid when applied too close together (within one hour). Keep in mind that "one hour" is different depending on how much product was used; if it's just a pea-sized amount of AHA or BHA then wait longer than if it were a dollop or two full pumps of something like glycolic acid or salicylic acid (which takes longer).

Do not mix Vitamin C with niacinamide.

Do not mix Vitamin C with niacinamide. Both vitamin C and niacinamide are antioxidants, but the two act in different ways. Niacinamide is a lipid-soluble antioxidant and works to prevent damage from free radicals in the skin’s lower layers (the dermis), whereas vitamin C acts on water-based structures above the epidermis. Therefore, you can use them together if you apply them at different times of day. For example, apply your vitamin C serum first thing in the morning before makeup and sunscreen, then wait until nighttime to add your niacinamide moisturizer or sunscreen product.

Do not mix Benzoyl peroxide and retinol together.

You can use retinol to treat acne and fine lines, but be aware that it can cause irritation. Benzoyl peroxide is a common ingredient in skincare products for treating acne, but it can also cause skin to become dry and irritated. If you use both of these together, they may react with each other and cause additional irritation on your skin.

To avoid this problem, apply benzoyl peroxide after washing off any retinol products from your face. Always keep them at least six hours apart so that they don't react with one another while sitting on top of your skin

Do not mix retinol and salicylic acid together.

Do not mix retinol and salicylic acid together.

Retinol is a form of vitamin A that's used to treat acne, reduce wrinkles, and lighten the skin. Salicylic acid is an exfoliant that can help treat acne.

The combination of these two products can cause irritation in your skin, which could lead to redness and dryness. To avoid this, make sure to use them at different times of day—for example, use your retinol overnight and apply your salicylic acid during the day. Or choose a product that contains both ingredients but has been formulated so they don't interact (like this one from Paula's Choice).

Do not combine alpha hydroxyl acids and peptides together.

Alpha hydroxyl acids and peptides are both used as moisturizers. Peptides can be considered protein fragments that work to promote skin elasticity, prevent wrinkles and fine lines, and improve the appearance of fine lines. Alpha hydroxyl acids are also used as moisturizers but they tend to be more powerful than peptides. Both are water-soluble so they should never be mixed together because they will neutralize each other's effects on your skin.

Do not combine alpha hydroxyl acids with benzoyl peroxide or salicylic acid.

If you have sensitive skin, you may want to take a second look at the ingredients in your skincare products. Avoid combining alpha hydroxyl acids (AHA) with benzoyl peroxide or salicylic acid. Both of these ingredients are chemical peels that can be irritating to sensitive skin, so it’s best to avoid using them together if you have this skin type.

Do not combine PHAs with BHAs or AHAs.

  • Do not combine PHAs with BHAs or AHAs.

  • Avoid using AHAs and PHAs at the same time, as they can irritate the skin.

  • Avoid using BHAs and AHAs at the same time, as they can irritate the skin.

  • Conclusion

In conclusion, it is important to know what ingredients cannot be mixed together. If you have sensitive skin or are looking for products that will not irritate your skin, then you should stick with those that are labeled "non-combinational." This means that they do not contain any ingredients which may conflict with each other and cause irritation or breakouts. It is also best not to mix different types of acids together unless the product specifically states otherwise (i.e., PHAs and BHAs).

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